Insulin Resistance Syndrome: Difference between revisions

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The '''insulin resistance syndrome''' is a "constellation of findings, including [[central obesity]], [[glucose intolerance]], [[dyslipidemia]], and [[hypertension]], that promotes the development of [[type 2 diabetes mellitus]], [[cardiovascular disease]], [[Cancer|cancer]], [[polycystic ovary syndrome|polysystic ovary syndrome]] (PCOS), and nonalcoholic fatty liver disease".(reference for quote: Sudha B. Biddinger & C. Ronald Kahn : FROM MICE TO MEN: Insights into the Insulin Resistance Syndromes.Annual Review of Physiology Vol. 68: 123-158 (Volume publication date January 2006) (doi:10.1146/annurev.physiol.68.040104.124723)). As [[Obesity|obesity]] has reached epidemic proportions in many countries of the developed world, a pattern of these findings has become recognized. Also called the metabolic syndrome, the dysmetabolic syndrome, or syndrome, this association of [[Physiology|physiologic findings]] is the focus of current research in [[medicine]].
The '''insulin resistance syndrome''' is a "constellation of findings, including [[central obesity]], [[glucose intolerance]], [[dyslipidemia]], and [[hypertension]], that promotes the development of [[type 2 diabetes mellitus]], [[cardiovascular disease]], [[Cancer|cancer]], [[polycystic ovary syndrome|polycystic ovary syndrome]] (PCOS), and nonalcoholic fatty liver disease".<ref name="pmid16460269">{{cite journal |author=Biddinger SB, Kahn CR |title=From mice to men: insights into the insulin resistance syndromes |journal=Annu. Rev. Physiol. |volume=68 |issue= |pages=123–58 |year=2006 |pmid=16460269 |doi=10.1146/annurev.physiol.68.040104.124723}}</ref>
 
As [[Obesity|obesity]] has reached epidemic proportions in many countries of the developed world, a pattern of these findings has become recognized. Also called the metabolic syndrome, the dysmetabolic syndrome, or syndrome X, this association of [[Physiology|physiologic findings]] is the focus of current research in [[medicine]].
 
== References ==
 
<references />

Revision as of 01:28, 13 November 2007


The insulin resistance syndrome is a "constellation of findings, including central obesity, glucose intolerance, dyslipidemia, and hypertension, that promotes the development of type 2 diabetes mellitus, cardiovascular disease, cancer, polycystic ovary syndrome (PCOS), and nonalcoholic fatty liver disease".[1]

As obesity has reached epidemic proportions in many countries of the developed world, a pattern of these findings has become recognized. Also called the metabolic syndrome, the dysmetabolic syndrome, or syndrome X, this association of physiologic findings is the focus of current research in medicine.

References

  1. Biddinger SB, Kahn CR (2006). "From mice to men: insights into the insulin resistance syndromes". Annu. Rev. Physiol. 68: 123–58. DOI:10.1146/annurev.physiol.68.040104.124723. PMID 16460269. Research Blogging.