Salmonella enterica: Difference between revisions

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==Description and significance==
==Description and significance==
''Salmonella enterica'' are rod shaped gram-negative bacteria. They are very commonly found in raw meat, chicken, and egg shells. Another one of its' habitats is in contaminated water. A famous example of one its' 2000 serovars is ''S. typhi,'' the cause of typhoid fever. Research done on the genomic sequencing of ''S. enterica'' can aid in the effectiveness of medications and vaccinations in treating disease. It is usually isolated on a selective medium such as Maconkey agar, XLD agar, XLT agar, or DCA agar. The three main serovars of ''Salmonella enterica'' are Typhi, Typhimurium, and Enteritidis. Their DNA are anywhere between 95% and 99% similar. Ways that researchers have used to differentiate between the different serovars is by looking at their phage specifity. ''S. typhi'' is the serovar responsible for typhoid fever, a lethal disease. This disease is usually found in poor, under developed areas. The most common symtoms are fever, vomiting and possible death. ''S. typhi'' is found in contaminated water. A human can become infected by drinking the contaminated water or even by washing other foods with the water. ''S. typhimurium'' used to be the most common cause of food poisining. It has many of the similar symptoms as ''S. typhi'' although not usually fatal. Humans with a weak immune system may require antiobiotics as treatment. ''S. enteritidis''has recently become the most common cause of food poisoning and causes the same symtoms as ''S. typhimurium.'' Additionally, it infects and spreads through flocks of chickens. This causes the Salmonella infection to affect the human intestines once the chicken has been ingested.
The Salmonella bacteria were first discovered by an American scientist, Dr. Daniel E. Salmon in 1884. Dr. Salmon isolated the bacteria from the intestines of a pig and called it ''Salmonella choleraesui.'' The genus Salmonella is divided into two species, ''S. enterica'' and ''S. bongori.'' ''Salmonella enterica'' are rod shaped gram-negative bacteria. They are very commonly found in raw meat, chicken, and egg shells. Another one of its' habitats is in contaminated water.Once it enters the host, it resides in the intstinal tract of the human or animal. Research done on the genomic sequencing of ''S. enterica'' can aid in the effectiveness of medications and vaccinations in treating disease. It is usually isolated on a selective medium such as Maconkey agar, XLD agar, XLT agar, or DCA agar. The three main serovars of ''Salmonella enterica'' are Typhi, Typhimurium, and Enteritidis. Their DNA are anywhere between 95% and 99% similar. Ways that researchers have used to differentiate between the different serovars is by looking at their phage specifity. ''S. typhi'' is the serovar responsible for typhoid fever, a lethal disease. This disease is usually found in poor, under developed areas. The most common symtoms are fever, vomiting and possible death. ''S. typhi'' is found in contaminated water. A human can become infected by drinking the contaminated water or even by washing other foods with the water. ''S. typhimurium'' used to be the most common cause of food poisining. It has many of the similar symptoms as ''S. typhi'' although not usually fatal. Humans with a weak immune system may require antiobiotics as treatment. ''S. enteritidis''has recently become the most common cause of food poisoning and causes the same symtoms as ''S. typhimurium.'' Additionally, it infects and spreads through flocks of chickens. This causes the Salmonella infection to affect the human intestines once the chicken has been ingested.


==Genome structure==
==Genome structure==

Revision as of 15:18, 26 March 2008

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Classification

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Higher order taxa

Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae

Species

Salmonella enterica

Description and significance

The Salmonella bacteria were first discovered by an American scientist, Dr. Daniel E. Salmon in 1884. Dr. Salmon isolated the bacteria from the intestines of a pig and called it Salmonella choleraesui. The genus Salmonella is divided into two species, S. enterica and S. bongori. Salmonella enterica are rod shaped gram-negative bacteria. They are very commonly found in raw meat, chicken, and egg shells. Another one of its' habitats is in contaminated water.Once it enters the host, it resides in the intstinal tract of the human or animal. Research done on the genomic sequencing of S. enterica can aid in the effectiveness of medications and vaccinations in treating disease. It is usually isolated on a selective medium such as Maconkey agar, XLD agar, XLT agar, or DCA agar. The three main serovars of Salmonella enterica are Typhi, Typhimurium, and Enteritidis. Their DNA are anywhere between 95% and 99% similar. Ways that researchers have used to differentiate between the different serovars is by looking at their phage specifity. S. typhi is the serovar responsible for typhoid fever, a lethal disease. This disease is usually found in poor, under developed areas. The most common symtoms are fever, vomiting and possible death. S. typhi is found in contaminated water. A human can become infected by drinking the contaminated water or even by washing other foods with the water. S. typhimurium used to be the most common cause of food poisining. It has many of the similar symptoms as S. typhi although not usually fatal. Humans with a weak immune system may require antiobiotics as treatment. S. enteritidishas recently become the most common cause of food poisoning and causes the same symtoms as S. typhimurium. Additionally, it infects and spreads through flocks of chickens. This causes the Salmonella infection to affect the human intestines once the chicken has been ingested.

Genome structure

Describe the size and content of the genome. How many chromosomes? Circular or linear? Other interesting features? What is known about its sequence? Does it have any plasmids? Are they important to the organism's lifestyle?

Cell structure and metabolism

S. enterica is a motile, rod shaped bacteria that contain flagella.

Ecology

Describe any interactions with other organisms (included eukaryotes), contributions to the environment, effect on environment, etc.

Pathology

Different species of Salmonella can cause a wide range of diseases from gastrointestinal problems to typhoid fever. Usually the strain can be carried in a large range hosts including humans, animals, rodents, and birds. S. typhi, a serovar of S. enterica, will only infect humans. The typhoid fever that it causes kills 500,000 people per year. Other serovars like S. typhimurium infect humans, as well as many other mammalian species. The bacteria enters the host by disturbing the membrane. Once inside, it harms the host by causing the levels of intracellular free calcium to increase and disorganizing the cytoplasm of the cell. Symptoms usually include diarrhea, fever, and abdominal cramps. Strains that are associated with food-borne infections are usually not treated with antibiotics, but will resolve themselves over time. The typhoidal strains usually do require treatment by antibiotics, and possibly hospitilization. Some of the antibiotics have been used in the beef and poultry industries. This has caused for a strain of bacteria to be resistant to the antibiotics.

Application to Biotechnology

Does this organism produce any useful compounds or enzymes? What are they and how are they used?

Current Research

Enter summaries of the most recent research here--at least three required

References

[Sample reference] Takai, K., Sugai, A., Itoh, T., and Horikoshi, K. "Palaeococcus ferrophilus gen. nov., sp. nov., a barophilic, hyperthermophilic archaeon from a deep-sea hydrothermal vent chimney". International Journal of Systematic and Evolutionary Microbiology. 2000. Volume 50. p. 489-500.