Hypothyroidism: Difference between revisions
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About thirty<ref name="pmid2394778">{{cite journal| author=Ross DS, Daniels GH, Gouveia D| title=The use and limitations of a chemiluminescent thyrotropin assay as a single thyroid function test in an out-patient endocrine clinic. | journal=J Clin Endocrinol Metab | year= 1990 | volume= 71 | issue= 3 | pages= 764-9 | pmid=2394778 | doi= | pmc= | url= }} </ref> to forty<ref name="pmid10695693">{{cite journal| author=Canaris GJ, Manowitz NR, Mayor G, Ridgway EC| title=The Colorado thyroid disease prevalence study. | journal=Arch Intern Med | year= 2000 | volume= 160 | issue= 4 | pages= 526-34 | pmid=10695693 | doi= | pmc= | url=http://archinte.ama-assn.org/cgi/content/full/160/4/526 }} </ref><ref name="pmid21109503">{{cite journal| author=Okosieme OE, Belludi G, Spittle K, Kadiyala R, Richards J| title=Adequacy of thyroid hormone replacement in a general population. | journal=QJM | year= 2011 | volume= 104 | issue= 5 | pages= 395-401 | pmid=21109503 | doi=10.1093/qjmed/hcq222 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21109503 }} </ref> percent of patients taking thyroid hormone replacement may not have appropriate values of [[thyroid stimulating hormone]] (TSH). | |||
Taking replacement hormone at night may be better.<ref name="pmid21149757">{{cite journal| author=Bolk N, Visser TJ, Nijman J, Jongste IJ, Tijssen JG, Berghout A| title=Effects of evening vs morning levothyroxine intake: a randomized double-blind crossover trial. | journal=Arch Intern Med | year= 2010 | volume= 170 | issue= 22 | pages= 1996-2003 | pmid=21149757 | doi=10.1001/archinternmed.2010.436 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21149757 }} </ref> | Taking replacement hormone at night may be better.<ref name="pmid21149757">{{cite journal| author=Bolk N, Visser TJ, Nijman J, Jongste IJ, Tijssen JG, Berghout A| title=Effects of evening vs morning levothyroxine intake: a randomized double-blind crossover trial. | journal=Arch Intern Med | year= 2010 | volume= 170 | issue= 22 | pages= 1996-2003 | pmid=21149757 | doi=10.1001/archinternmed.2010.436 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21149757 }} </ref> | ||
Revision as of 15:33, 27 July 2011
In medicine, hypothyroidism is "a syndrome that results from abnormally low secretion of thyroid hormones from the thyroid gland, leading to a decrease in basal metabolic rate. In its most severe form, there is accumulation of mucopolysaccharides in the skin and edema, known as myxedema."[1]
Thyroid stimulating hormone levels of less than 10 may not be important.[2]
Diagnosis
Symptoms
Symptoms may not be accurate.[3][4] The symptoms that may be distinguish between hypothyroid and normal patients are hoarse voice, dry skin, and muscle cramps.[4]
Treatment
About thirty[5] to forty[3][6] percent of patients taking thyroid hormone replacement may not have appropriate values of thyroid stimulating hormone (TSH).
Taking replacement hormone at night may be better.[7]
References
- ↑ Anonymous (2024), Hypothyroidism (English). Medical Subject Headings. U.S. National Library of Medicine.
- ↑ Rodondi N, den Elzen WP, Bauer DC, Cappola AR, Razvi S, Walsh JP et al. (2010). "Subclinical hypothyroidism and the risk of coronary heart disease and mortality.". JAMA 304 (12): 1365-74. DOI:10.1001/jama.2010.1361. PMID 20858880. Research Blogging.
- ↑ 3.0 3.1 Canaris GJ, Manowitz NR, Mayor G, Ridgway EC (2000). "The Colorado thyroid disease prevalence study.". Arch Intern Med 160 (4): 526-34. PMID 10695693. [e]
- ↑ 4.0 4.1 Canaris GJ, Steiner JF, Ridgway EC (1997). "Do traditional symptoms of hypothyroidism correlate with biochemical disease?". J Gen Intern Med 12 (9): 544-50. DOI:10.1046/j.1525-1497.1997.07109.x. PMID 9294788. PMC PMC1497160. Research Blogging.
- ↑ Ross DS, Daniels GH, Gouveia D (1990). "The use and limitations of a chemiluminescent thyrotropin assay as a single thyroid function test in an out-patient endocrine clinic.". J Clin Endocrinol Metab 71 (3): 764-9. PMID 2394778. [e]
- ↑ Okosieme OE, Belludi G, Spittle K, Kadiyala R, Richards J (2011). "Adequacy of thyroid hormone replacement in a general population.". QJM 104 (5): 395-401. DOI:10.1093/qjmed/hcq222. PMID 21109503. Research Blogging.
- ↑ Bolk N, Visser TJ, Nijman J, Jongste IJ, Tijssen JG, Berghout A (2010). "Effects of evening vs morning levothyroxine intake: a randomized double-blind crossover trial.". Arch Intern Med 170 (22): 1996-2003. DOI:10.1001/archinternmed.2010.436. PMID 21149757. Research Blogging.