Entecavir: Difference between revisions

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{{Chem infobox
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== Chemistry ==
== Chemistry ==
Its IUPAC chemical name is 2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-3H-purin-6-one and it has chemical formula C<sub>12</sub>H<sub>15</sub>N<sub>5</sub>O<sub>3</sub>.
Its [[IUPAC]] chemical name is 2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-3H-purin-6-one and it has chemical formula C<sub>12</sub>H<sub>15</sub>N<sub>5</sub>O<sub>3</sub>.


==External links ==
==External links ==
* {{DailyMed}}
{{CZMed}}[[Category:Suggestion Bot Tag]]
* {{MedMaster}}
* {{DrugBank}}

Latest revision as of 17:00, 12 August 2024

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entecavir
IUPAC name: see chemistry section
Synonyms: Baraclude®
Formula: C12H15N5O3

 Uses: Hepatitis B

 Properties: guanine analog, polymerase inhibitor

 Hazards: see drug interactions

Mass (g/mol): CAS #:
277.2792 142217-69-4


Entecavir, sold under the brand name Baraclude® is an oral antiviral drug used to treat hepatitis B infection. Entecavir is a guanine analogue that inhibits all three steps in the viral replication process, and the manufacturer claims that it is more efficacious than previous agents used to treat hepatitis B (lamivudine and adefovir). In the triphosphate form, it competes with the natural DNA base deoxyguanosine triphosphate (dGTP) for incorporation into the negative and positive strand DNA synthesis.

Chemistry

Its IUPAC chemical name is 2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-3H-purin-6-one and it has chemical formula C12H15N5O3.

External links

The most up-to-date information about Entecavir and other drugs can be found at the following sites.