Bioavailability: Difference between revisions
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'''Bioavailability''' is the degree to which a drug, nutrient or other biologically active substance becomes available to the target tissue after administration. <ref name=Cancerweb>{{citation | In [[pharmacology]], '''Bioavailability''' is the degree to which a drug, nutrient or other biologically active substance becomes available to the target tissue after administration. <ref name=Cancerweb>{{citation | ||
| title = Bioavailability | | title = Bioavailability | ||
| url = http://cancerweb.ncl.ac.uk/cgi-bin/omd?bioavailability}}</ref> For bioavailability to be verified, there must be a chemical, biological, immunologic, or other test that verifies the concentration of the drug, or its active derivative, in the body fluids of the recipient. | | url = http://cancerweb.ncl.ac.uk/cgi-bin/omd?bioavailability}}</ref> For bioavailability to be verified, there must be a chemical, biological, immunologic, or other test that verifies the concentration of the drug, or its active derivative, in the body fluids of the recipient. | ||
'''Bioequivalence''' covers the case where the initial distribution of different drug preparations may vary, but the duration and form of the active principle is delivered identically. <ref>{{citation | '''Bioequivalence''' covers the case where the initial distribution of different drug preparations may vary, but the duration and form of the active principle is delivered identically. <ref>{{citation | ||
| title = US Code of Federal Regulations | | title = US Code of Federal Regulations | ||
Revision as of 00:56, 11 June 2010
In pharmacology, Bioavailability is the degree to which a drug, nutrient or other biologically active substance becomes available to the target tissue after administration. [1] For bioavailability to be verified, there must be a chemical, biological, immunologic, or other test that verifies the concentration of the drug, or its active derivative, in the body fluids of the recipient.
Bioequivalence covers the case where the initial distribution of different drug preparations may vary, but the duration and form of the active principle is delivered identically. [2]
References
- ↑ Bioavailability
- ↑ , Subcapter D, Drugs for Human Use, Part 320: Bioavailability and Bioequivalence requirements, US Code of Federal Regulations, April 1, 2008, 21CFR320.24