Parainfluenza virus: Difference between revisions

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==Description and significance==
==Description and significance==


Parainfluenza refers to a group of viruses that cause upper and lower respiratory infections.   Human parainfluenza viruses (HPIVs) are paramyxoviruses and are second to respiratory syncytial virus (RSV) as a most common cause of upper and lower respiratory tract infections especially in infants and young children <ref>http://en.wikipedia.org/wiki/Parainfluenza_virus</ref>. It is less common in adults.
Upper and lower respiratory tract diseases in humans are mostly caused by Human parainfluenze viruses and as a group are called “parainfluenza.Human parainfluenza viruses (HPIVs) are the second to the respiratory syntial virus (RSV) as a common cause of upper and lower respiratory tract infections especially in infants and young children. <ref> http://en.wikipedia.org/wiki/Parainfluenza_virus </ref>  It is less common among adults.
Paramyxoviruses are viruses of the Paramyxoviridae family of the Mononegavirales order; they are negative-sense single-stranded RNA (-ssRNA) viruses responsible for a number of human and animal diseases. Negative-sense ssRNA viruses must have their genome copied by an RNA polymerase to form positive-sense RNA. This means that the virus must bring along with it the RNA-dependent RNA polymerase enzyme. The positive-sense RNA molecule then acts as viral mRNA, which is translated into proteins by the host ribosomes. The resultant protein goes on to direct the synthesis of new virions, such as capsid proteins and RNA replicase, which is used to produce new negative-sense RNA molecules.
Paramyxoviruses belong to Paramyxoviridae family of Mononegavirales order which are negative sense single stranded RNA (-ssRNA) viruses responsible for many diseases in humans and animals. Negative sense RNA first of all makes positive sense RNA through copying their genomes by RNA polymerase. The positive sense RNA molecule is translated into proteins acting as viral mRNA. Thus more –ssRNA are produced when the resultant proteins directs the synthesis of new virions such as capsid proteins and RNA repilcases. <ref>http://en.wikipedia.org/wiki/Negative-sense_virus</ref>


==Genome structure==
==Genome structure==

Revision as of 22:21, 17 April 2009

Human Parainfluenza Virus
Parainfluenza virus.jpg
Virus classification
Group: ssRNA

Description and significance

Upper and lower respiratory tract diseases in humans are mostly caused by Human parainfluenze viruses and as a group are called “parainfluenza.” Human parainfluenza viruses (HPIVs) are the second to the respiratory syntial virus (RSV) as a common cause of upper and lower respiratory tract infections especially in infants and young children. [1] It is less common among adults. Paramyxoviruses belong to Paramyxoviridae family of Mononegavirales order which are negative sense single stranded RNA (-ssRNA) viruses responsible for many diseases in humans and animals. Negative sense RNA first of all makes positive sense RNA through copying their genomes by RNA polymerase. The positive sense RNA molecule is translated into proteins acting as viral mRNA. Thus more –ssRNA are produced when the resultant proteins directs the synthesis of new virions such as capsid proteins and RNA repilcases. [2]

Genome structure

Cell structure and metabolism

Ecology

Pathology

Application to Biotechnology

Current Research

References

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