Diabesity: Difference between revisions
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<ref>"Part 2," Appetite and obesity. 2006. Retrieved July 21, 2009 from [http://www.appetiteandobesity.org/part2.html http://www.appetiteandobesity.org/part2.html]</ref> | <ref>"Part 2," Appetite and obesity. 2006. Retrieved July 21, 2009 from [http://www.appetiteandobesity.org/part2.html http://www.appetiteandobesity.org/part2.html]</ref> | ||
==The immunology of obesity== | ==The immunology of obesity== by Luke Kennedy Burke | ||
Type 2 diabetes has long been thought of as primarily a metabolic disease. A series of recent studies have challenged this dogma and implicated an unlikely candidate system in the promotion of disease onset - the immune system. Mild inflammation of fat tissue in obese patients reportedly acts through immune-cell processes to impair insulin signalling in adipocytes. This work therefore provides a novel way of understanding the link between obesity and type 2 diabetes. | Type 2 diabetes has long been thought of as primarily a metabolic disease. A series of recent studies have challenged this dogma and implicated an unlikely candidate system in the promotion of disease onset - the immune system. Mild inflammation of fat tissue in obese patients reportedly acts through immune-cell processes to impair insulin signalling in adipocytes. This work therefore provides a novel way of understanding the link between obesity and type 2 diabetes. | ||
Revision as of 10:23, 13 October 2009
This page was started in the framework of an Eduzendium course and needs to be assessed for quality. If this is done, this {{EZnotice}} can be removed.
A brief overview of your interest group (be sure to put its name in bold in the first sentence) and the scope of the article goes here.[1]
The following list of sections should serve as a loose guideline for developing the body of your article. The works cited in references 2-5 are all fake; their purpose is to serve as a formatting model for your own citations.
Title of Part 1
Title of Subpart 1
In here you could write about various informations linked to various references for example from journals. [2] [3]
Title of Subpart 2
You can also insert diagram.
Title of Part 2
You can also cite published work accessible online. [4]
==The immunology of obesity== by Luke Kennedy Burke
Type 2 diabetes has long been thought of as primarily a metabolic disease. A series of recent studies have challenged this dogma and implicated an unlikely candidate system in the promotion of disease onset - the immune system. Mild inflammation of fat tissue in obese patients reportedly acts through immune-cell processes to impair insulin signalling in adipocytes. This work therefore provides a novel way of understanding the link between obesity and type 2 diabetes.
Key References
Normalization of obesity-associated insulin resistance through immunotherapy http://www.nature.com/nm/journal/v15/n8/full/nm.2001.html
Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice http://www.nature.com/nm/journal/v15/n8/full/nm.1994.html
Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters http://www.nature.com/nm/journal/v15/n8/full/nm.2002.html
CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity http://www.nature.com/nm/journal/v15/n8/full/nm.1964.html
The protein kinase IKKepsilon regulates energy balance in obese mice http://www.cell.com/retrieve/pii/S0092867409007934
T-ing up inflammation in fat http://www.nature.com/nm/journal/v15/n8/full/nm0809-846.html
References
- ↑ See the "Writing an Encyclopedia Article" handout for more details.
- ↑ First Author and Second Author, "The perfect reference for Subpart 1," Fake Journal of Neuroendocrinology 36:2 (2015) pp. 36-52.
- ↑ First Author and Second Author, "Another perfect reference for Subpart 1," Fake Journal of Neuroendocrinology 25:2 (2009) pp. 62-99.
- ↑ "Part 2," Appetite and obesity. 2006. Retrieved July 21, 2009 from http://www.appetiteandobesity.org/part2.html