Talk:Antimalarial: Difference between revisions

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imported>Sandy Harris
imported>Howard C. Berkowitz
 
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: Quinine derivatives? [[User:Sandy Harris|Sandy Harris]] 16:32, 28 May 2010 (UTC)
: Quinine derivatives? [[User:Sandy Harris|Sandy Harris]] 16:32, 28 May 2010 (UTC)
::Closer to "quinine and synthetic substitutes", although I need to look at the structural formulas. As I remember, the three synthetics aren't that close to the molecular structure of quinine. [[User:Howard C. Berkowitz|Howard C. Berkowitz]] 17:28, 28 May 2010 (UTC)

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 Definition Rather than all drugs active against malaria, usually a reference to several synthetic analogues of quinine, with applications against malaria and other parasites, but also as disease modifying anti-rheumatic drugs (DMARD) used as immunomodulators in rheumatology [d] [e]
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Not happy with the title of this article...but what is better?

These really are called "antimalarials" by the rheumatology and immunology folk. Yes, they act against malaria, and chloroquine is still an important drug, but I'm concerned that a layman would assume these are the only drugs active against malaria. The range of available drugs is in the malaria article -- would a "see also" be good enough?

Otherwise, the best alternative title I've considered is "synthetic quinine replacements", which is not intuitive to many.

Yes, I should probably have structural formulas, and of quinine as well. First, I have to dig into my email and find the name of the freeware chemical drawing package; I might need help on quinine, which has a somewhat unusual structure. Yes, I'm reviewing my organic chemistry.

Suggestions? --Howard C. Berkowitz 13:57, 28 May 2010 (UTC)

Quinine derivatives? Sandy Harris 16:32, 28 May 2010 (UTC)
Closer to "quinine and synthetic substitutes", although I need to look at the structural formulas. As I remember, the three synthetics aren't that close to the molecular structure of quinine. Howard C. Berkowitz 17:28, 28 May 2010 (UTC)