Selenium

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Selenium is a chemical element, having the chemical symbol Se.

Selenium
78.96(3)



  Se
34
[Ar] 4s2 3d10 4p4
[ ? ] Non-Metal:

Its atomic number (the number of protons) is 34. It has a Standard Atomic Weight of 78.96(3), and is typically found as a solid in its elemental form.

Selenium is considered to be a member of the "Non-Metal" class of elements, has a boiling point of 685 °C , and a melting point of 220.5 °C .

Role in health

Deficiency of selenium may cause heart failure.[1] This may occur in the settings or anorexia nervosa[2], bariatric surgery[3], peripartum cardiomyopathy[4] and Keshan Disease. However, while selenium levels are lower among patients with heart failure than among controls, levels are similarly decreased whether heart failure is idiopathic or ischemic.[5] A small randomized controlled trial showed benefit from micronutrient supplementation that included selenium.[6]

Deficiency of selenium may cause coronary heart disease[7]

References

  1. Saliba W, El Fakih R, Shaheen W (2010). "Heart failure secondary to selenium deficiency, reversible after supplementation.". Int J Cardiol 141 (2): e26-7. DOI:10.1016/j.ijcard.2008.11.095. PMID 19059654. Research Blogging.
  2. Birmingham CL, Gritzner S (2007). "Heart failure in anorexia nervosa: case report and review of the literature.". Eat Weight Disord 12 (1): e7-10. PMID 17384523[e]
  3. Boldery R, Fielding G, Rafter T, Pascoe AL, Scalia GM (2007). "Nutritional deficiency of selenium secondary to weight loss (bariatric) surgery associated with life-threatening cardiomyopathy.". Heart Lung Circ 16 (2): 123-6. DOI:10.1016/j.hlc.2006.07.013. PMID 17324623. Research Blogging.
  4. Cénac A, Touré K, Diarra MB, Sergeant C, Jobic Y, Sanogo K et al. (2004). "[Plasma selenium and peripartum cardiomyopathy in Bamako, Mali].". Med Trop (Mars) 64 (2): 151-4. PMID 15460143[e]
  5. Koşar F, Sahin I, Taşkapan C, Küçükbay Z, Güllü H, Taşkapan H et al. (2006). "Trace element status (Se, Zn, Cu) in heart failure.". Anadolu Kardiyol Derg 6 (3): 216-20. PMID 16943104[e]
  6. Witte KK, Nikitin NP, Parker AC, von Haehling S, Volk HD, Anker SD et al. (2005). "The effect of micronutrient supplementation on quality-of-life and left ventricular function in elderly patients with chronic heart failure.". Eur Heart J 26 (21): 2238-44. DOI:10.1093/eurheartj/ehi442. PMID 16081469. Research Blogging.
  7. Flores-Mateo G, Navas-Acien A, Pastor-Barriuso R, Guallar E (2006). "Selenium and coronary heart disease: a meta-analysis.". Am J Clin Nutr 84 (4): 762-73. PMID 17023702. PMC PMC1829306[e]