Anthrax: Difference between revisions

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imported>Howard C. Berkowitz
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===General measures===
===General measures===
===Immunization===
===Immunization===
Immunization is not recommended for the general population, although it is routinely given to military personnel, and to laboratory and clinical workers at high risk. There have been manufacturing and efficacy problems with the vaccine.
===Chemoprophylaxis===
===Chemoprophylaxis===
 
While the native agent is penicillin-sensitive, it is assumed that weaponized agents will be resistant. The first-choice prophylactic drug is [[ciprofloxacin]], with [[doxycycline]] as a reasonable alternative.
==Clinical Presentation==
==Clinical Presentation==
===Forms of the disease===
===Forms of the disease===

Revision as of 02:46, 17 August 2010

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Anthrax is a potentially lethal bacterial infection caused by Bacillus anthracis. It is endemic among animals, and is of great concern as the effect of biological warfare or bioterrorism using B. anthracis as the pathogen.

Prevention

General measures

Immunization

Immunization is not recommended for the general population, although it is routinely given to military personnel, and to laboratory and clinical workers at high risk. There have been manufacturing and efficacy problems with the vaccine.

Chemoprophylaxis

While the native agent is penicillin-sensitive, it is assumed that weaponized agents will be resistant. The first-choice prophylactic drug is ciprofloxacin, with doxycycline as a reasonable alternative.

Clinical Presentation

Forms of the disease

  • cutaneous
  • gastrontestinal
  • pneumonic

Differential diagnosis

Physical examination

Laboratory presentation

Treatment and prognosis

Significant outbreaks and cases

  • Sverdlovsk incident
  • African drum-makers

References