Astrocytoma: Difference between revisions
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imported>Howard C. Berkowitz (New page: {{subpages}} In neurology and oncology, an '''astrocytoma'' is a neoplasm of the central nervous system, which originates in normal astrocytes. Under the 1993 [[World H...) |
imported>Meg Taylor No edit summary |
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In [[neurology]] and [[oncology]], an '''astrocytoma'' is a [[neoplasm]] of the [[central nervous system]], which originates in normal [[astrocyte]]s. Under the 1993 [[World Health Association]] criteria, a [[glioblastoma]] can be considered a "high-grade" (Grade IV) astrocytoma; grade III anaplastic astrocytomas are also malignant. The lower-grade astrocytomas may progress to higher-grade <ref>{{citation | In [[neurology]] and [[oncology]], an '''astrocytoma''' is a [[neoplasm]] of the [[central nervous system]], which originates in normal [[astrocyte]]s. Under the 1993 [[World Health Association]] criteria, a [[glioblastoma]] can be considered a "high-grade" (Grade IV) astrocytoma; grade III anaplastic astrocytomas are also malignant. The lower-grade astrocytomas may progress to higher-grade <ref>{{citation | ||
| title = The new WHO Classification of Tumors affecting the Central Nervous System | | title = The new WHO Classification of Tumors affecting the Central Nervous System | ||
| author = Stephen B. Tatter | | author = Stephen B. Tatter | ||
| url = http://neurosurgery.mgh.harvard.edu/newwhobt.htm | |||
| year = 2006 | | year = 2006 | ||
| publisher = Neurosurgical Service, [[ | | publisher = Neurosurgical Service, [[Massachusetts General Hospital]]}}</ref> | ||
{| class="wikitable" | {| class="wikitable" | ||
| Line 24: | Line 25: | ||
| I, II | | I, II | ||
| 1 or 2 | | 1 or 2 | ||
| 1: No criteria fulfilled; 2: one | | 1: No criteria fulfilled; 2: one criterion, usually nuclear atypia | ||
|- | |- | ||
|Anaplastic | |Anaplastic | ||
Latest revision as of 06:34, 28 September 2013
In neurology and oncology, an astrocytoma is a neoplasm of the central nervous system, which originates in normal astrocytes. Under the 1993 World Health Association criteria, a glioblastoma can be considered a "high-grade" (Grade IV) astrocytoma; grade III anaplastic astrocytomas are also malignant. The lower-grade astrocytomas may progress to higher-grade [1]
| WHO designation | WHO grade | Kernohan grade | St. Anne/Mayo grade | St. Anne/Mayo criteria |
|---|---|---|---|---|
| pilocytic astrocytoma | I | I | excluded | |
| Astrocytoma | II | I, II | 1 or 2 | 1: No criteria fulfilled; 2: one criterion, usually nuclear atypia |
| Anaplastic | II | II, III | 3 | Two criteria: nuclear atypia and mitosis |
| Malignant astrocytoma and glioblastoma | IV | III, IV | 4 | Three or four; add necrosis |
References
- ↑ Stephen B. Tatter (2006), The new WHO Classification of Tumors affecting the Central Nervous System, Neurosurgical Service, Massachusetts General Hospital