Chlamydia trachomatis: Difference between revisions

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==Cell structure and metabolism==
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''Chlamydia trachomatis'' is structurally [[gram negative]] and is one of three bacterial species in the genus ''Chlamydia''.  It was once thought to be a virus because it could have not been cultured in an artificial medium. ''C. trachomatis'' is an obligate intracellular pathogen that lives within human cells and cannot make its own [[ATP]].  This means that they are unable to replicate outside of a host cell.  The pathogens have evolved a unique biphasic life cycle.  They alternate between two functionally and morphologically distinct forms; elementary body and reticular body.  Elementary body (EB) is infectious, but metabolically inert (chemically inactive).  EB is taken up by host cells, primarily byreceptor-mediated endocytosis.  the bacteria prevent fusion of the endosome and lysosome, but the mechanism of this is not known.  Inside the endosome, the EB differentiates into a metabolically active but non-infectious form, reticulate body (RB) using energy sources and amino acids from the host cell.  RB replicates and ultimately forms new EBs that are capable of infecting additional cells.  ''C. trachomatis'' has a glycolytic pathway and a linked tricarboxylic acid cycle. Glycogen synthesis and use of glucose derivatives plays a supporting role in chlamydial metabolism.
{{Taxobox
| color = pink
| name = 
| image =
| regnum = Eubacteria
| phylum =
| classis =  Chlamydiae
| ordo =  Chlamydiales
| familia =  Chlamydiaceae
| genus =   Chlamydia
| species = trachomatis
| Binomial = ''C. trachomatis''
}}
 
'''''Chlamydia trachomatis''''' is a pathogen that causes many serious health threats to humans.  Chlamydia is one of the most common STD which is caused by chlamydia trachomatis.  An estimated 4 million C. trachomatis infections occur annually among the sexually active population in the United States.  The majority of persons with C. trachomatis infection are not aware of their infection because they do not have symptoms.  The infection is easily cured if diagnosed, but many infections remain untreated and lead to other illnesses such as infertility in both men and women.  Another disease caused by C. trachomatis is trachoma, most common cause of blindness among children in Africa and other developing nations.

Latest revision as of 17:45, 9 June 2009

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Scientific classification
Kingdom: Eubacteria
Class: Chlamydiae
Order: Chlamydiales
Family: Chlamydiaceae
Genus: Chlamydia
Species: trachomatis

Chlamydia trachomatis is a pathogen that causes many serious health threats to humans. Chlamydia is one of the most common STD which is caused by chlamydia trachomatis. An estimated 4 million C. trachomatis infections occur annually among the sexually active population in the United States. The majority of persons with C. trachomatis infection are not aware of their infection because they do not have symptoms. The infection is easily cured if diagnosed, but many infections remain untreated and lead to other illnesses such as infertility in both men and women. Another disease caused by C. trachomatis is trachoma, most common cause of blindness among children in Africa and other developing nations.

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