Complex regional pain syndrome

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In pain medicine, Complex regional pain syndrome encompasses several "Conditions characterized by pain involving an extremity or other body region, hyperesthesia, and localized autonomic dysfunction following injury to soft tissue or nerve. The pain is usually associated with reddening of the skin (erythema); skin temperature changes, abnormal sudomotor activity (i.e., changes in sweating due to altered sympathetic innervation) or edema. The degree of pain and other manifestations is out of proportion to that expected from the inciting event. Two subtypes of this condition have been described:

These are chronic pain conditions.

  1. Anonymous (2024), Complex regional pain syndrome (English). Medical Subject Headings. U.S. National Library of Medicine. From Pain 1995 Oct;63(1):127-33)