Erythrocyte transfusion: Difference between revisions

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(New page: {{subpages}} In medicine, '''erythrocyte transfusion''' or '''red blood cell transfusion''' is the "transfer of erythrocytes from a donor to a recipient or reinfusion to the donor."<re...)
 
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In [[medicine]], '''erythrocyte transfusion''' or '''red blood cell transfusion''' is the "transfer of erythrocytes from a donor to a recipient or reinfusion to the donor."<ref>{{MeSH}}</ref>
In [[medicine]], '''erythrocyte transfusion''' or '''red blood cell transfusion''' is the "transfer of [[erythrocyte]]s from a donor to a recipient or reinfusion to the donor."<ref>{{MeSH}}</ref>


==Adverse effects==
==Adverse effects==
===Blood group incompatibility===
===Immunologic reactions===
A blood group incompatibility is a "mismatch between donor and recipient blood. [[Antibody|Antibodies]] present in the recipient's serum are directed against [[antigen]]s in the donor product. Such a mismatch may result in a transfusion reaction in which, for example, donor blood is hemolyzed."<ref>{{MeSH|Blood group incompatibility}}</ref>
* '''Febrile nonhemolytic transfusion reactions (FNHTR)''' due to destruction of incompatible donor white blood cells
* '''Hemolytic reactions''' due to [[blood group incompatibility]] is "mismatch between donor and recipient blood. [[Antibody|Antibodies]] present in the recipient's serum are directed against [[antigen]]s in the donor product. Such a mismatch may result in a transfusion reaction in which, for example, donor blood is hemolyzed."<ref>{{MeSH|Blood group incompatibility}}</ref>
** Acute hemolytic transfusion reactions due to ABO incompatibility
** Delayed hemolytic transfusion reactions
* '''Allergic reactions'''
** Anaphylactic transfusion reactions may occur, especially in patients with IgA-deficiency.
** Urticaria may occur due to the recipient's IgE reacting to antigens from the donor.
* '''Posttransfusion purpura (PTP)''' due to thrombocytopenia from platelet antibodies. This is more common in women who have been pregnant.
* Transfusion associated graft-versus-host disease (TA-GVHD)


===Chemical reactions===
* Hemosiderosis
* Hypocalcemia from citrate toxicity
* Hyperkalemia
* Metabolic alkalosis and hypokalemia due to citrate
===Transfusion-related acute lung injury (pulmonary leukoagglutinin reaction)===
===Transmission of infection===
===Other reactions===
* Hypothermia
* Circulatory overload


==References==
==References==
<references/>
<references/>
==External links==
* [http://www.isbt-web.org/ International Society of Blood Transfusion (ISBT)]
* Dean L. (2005) [http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=rbcantigen Blood Groups and Red Cell Antigens] NCBI
** [http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=rbcantigen&part=ch3 Blood transfusions and the immune system]

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In medicine, erythrocyte transfusion or red blood cell transfusion is the "transfer of erythrocytes from a donor to a recipient or reinfusion to the donor."[1]

Adverse effects

Immunologic reactions

  • Febrile nonhemolytic transfusion reactions (FNHTR) due to destruction of incompatible donor white blood cells
  • Hemolytic reactions due to blood group incompatibility is "mismatch between donor and recipient blood. Antibodies present in the recipient's serum are directed against antigens in the donor product. Such a mismatch may result in a transfusion reaction in which, for example, donor blood is hemolyzed."[2]
    • Acute hemolytic transfusion reactions due to ABO incompatibility
    • Delayed hemolytic transfusion reactions
  • Allergic reactions
    • Anaphylactic transfusion reactions may occur, especially in patients with IgA-deficiency.
    • Urticaria may occur due to the recipient's IgE reacting to antigens from the donor.
  • Posttransfusion purpura (PTP) due to thrombocytopenia from platelet antibodies. This is more common in women who have been pregnant.
  • Transfusion associated graft-versus-host disease (TA-GVHD)

Chemical reactions

  • Hemosiderosis
  • Hypocalcemia from citrate toxicity
  • Hyperkalemia
  • Metabolic alkalosis and hypokalemia due to citrate

Transfusion-related acute lung injury (pulmonary leukoagglutinin reaction)

Transmission of infection

Other reactions

  • Hypothermia
  • Circulatory overload

References

  1. ↑ Anonymous (2024), Erythrocyte transfusion (English). Medical Subject Headings. U.S. National Library of Medicine.
  2. ↑ Anonymous (2024), Blood group incompatibility (English). Medical Subject Headings. U.S. National Library of Medicine.

External links

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