Hypoalphalipoproteinemia: Difference between revisions
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imported>Robert Badgett (New page: '''Hypoalphalipoproteinemia''', also called ''familial high density lipoprotein deficiency disease'' and ''HDL lipoprotein deficiency disease'', is defined as "conditions with abnormally l...) |
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''' | '''Hypoalphalipoproteinemias''', also called ''familial high density lipoprotein deficiency disease'' and ''HDL lipoprotein deficiency disease'', are defined as "conditions with abnormally low levels of alpha-lipoproteins (high-density lipoproteins) in the blood. Hypoalphalipoproteinemia can be associated with mutations in genes encoding apolipoprotein a-i; lecithin cholesterol acyltransferase; and atp-binding cassette transporters."<ref name="MeSH-Hypoalphalipoproteinemias ">{{cite web |url=http://www.nlm.nih.gov/cgi/mesh/2008/MB_cgi?term=Hypoalphalipoproteinemias |title=Hypoalphalipoproteinemias |accessdate=2007-12-17 |author=National Library of Medicine |authorlink= |coauthors= |date= |format= |work= |publisher= |pages= |language= |archiveurl= |archivedate= |quote=}}</ref> | ||
==Treatment== | |||
Using [[gemfibrozil]] to treat hypoalphalipoproteinemia may reduce [[stroke]] in men with known men with known [[coronary heart disease]].<ref name="pmid11401940">{{cite journal |author=Bloomfield Rubins H, Davenport J, Babikian V, ''et al'' |title=Reduction in stroke with gemfibrozil in men with coronary heart disease and low HDL cholesterol: The Veterans Affairs HDL Intervention Trial (VA-HIT) |journal=Circulation |volume=103 |issue=23 |pages=2828–33 |year=2001 |pmid=11401940 |doi= |issn=}}</ref> | |||
==References== | ==References== | ||
Revision as of 17:42, 17 December 2007
Hypoalphalipoproteinemias, also called familial high density lipoprotein deficiency disease and HDL lipoprotein deficiency disease, are defined as "conditions with abnormally low levels of alpha-lipoproteins (high-density lipoproteins) in the blood. Hypoalphalipoproteinemia can be associated with mutations in genes encoding apolipoprotein a-i; lecithin cholesterol acyltransferase; and atp-binding cassette transporters."[1]
Treatment
Using gemfibrozil to treat hypoalphalipoproteinemia may reduce stroke in men with known men with known coronary heart disease.[2]
References
- ↑ National Library of Medicine. Hypoalphalipoproteinemias. Retrieved on 2007-12-17.
- ↑ Bloomfield Rubins H, Davenport J, Babikian V, et al (2001). "Reduction in stroke with gemfibrozil in men with coronary heart disease and low HDL cholesterol: The Veterans Affairs HDL Intervention Trial (VA-HIT)". Circulation 103 (23): 2828–33. PMID 11401940. [e]