Hypoalphalipoproteinemia
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Hypoalphalipoproteinemias, also called familial high density lipoprotein deficiency disease and HDL lipoprotein deficiency disease, are defined as "conditions with abnormally low levels of alpha-lipoproteins (high-density lipoproteins) in the blood. Hypoalphalipoproteinemia can be associated with mutations in genes encoding apolipoprotein a-i; lecithin cholesterol acyltransferase; and atp-binding cassette transporters."[1]
Treatment
Using gemfibrozil to treat hypoalphalipoproteinemia may reduce stroke in men with known men with known coronary heart disease.[2]
References
- ↑ National Library of Medicine. Hypoalphalipoproteinemias. Retrieved on 2007-12-17.
- ↑ Bloomfield Rubins H, Davenport J, Babikian V, et al (2001). "Reduction in stroke with gemfibrozil in men with coronary heart disease and low HDL cholesterol: The Veterans Affairs HDL Intervention Trial (VA-HIT)". Circulation 103 (23): 2828–33. PMID 11401940. [e]