Lipoprotein: Difference between revisions
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In [[medicine]] and [[biochemistry]], '''lipoproteins''' are "lipid-protein complexes involved in the transportation and metabolism of lipids in the body. They are spherical particles consisting of a hydrophobic core of [[triglyceride]]s and [[cholesterol ester]]s surrounded by a layer of hydrophilic free [[cholesterol]]; [[phospholipid]]s; and [[apolipoprotein]]s. Lipoproteins are classified by their varying buoyant density and sizes. The large lipoproteins ([[chylomicron]]s; VLDL) are to transport triglycerides, and the small lipoproteins (LDL; HDL) are to transport cholesterol."<ref>{{MeSH}}</ref> | In [[medicine]] and [[biochemistry]], '''lipoproteins''' are "lipid-protein complexes involved in the transportation and metabolism of lipids in the body. They are spherical particles consisting of a hydrophobic core of [[triglyceride]]s and [[cholesterol ester]]s surrounded by a layer of hydrophilic free [[cholesterol]]; [[phospholipid]]s; and [[apolipoprotein]]s. Lipoproteins are classified by their varying buoyant density and sizes. The large lipoproteins ([[chylomicron]]s; VLDL) are to transport triglycerides, and the small lipoproteins (LDL; HDL) are to transport cholesterol."<ref>{{MeSH}}</ref> | ||
Latest revision as of 17:11, 30 January 2010
In medicine and biochemistry, lipoproteins are "lipid-protein complexes involved in the transportation and metabolism of lipids in the body. They are spherical particles consisting of a hydrophobic core of triglycerides and cholesterol esters surrounded by a layer of hydrophilic free cholesterol; phospholipids; and apolipoproteins. Lipoproteins are classified by their varying buoyant density and sizes. The large lipoproteins (chylomicrons; VLDL) are to transport triglycerides, and the small lipoproteins (LDL; HDL) are to transport cholesterol."[1]
Classification
Lipoproteins that are normally present.
- HDL lipoproteins (alpha lipoproteins) contain HDL cholesterol. Low levels are found in the familial disorders hypoalphalipoproteinemias.
- IDL lipoproteins
- LDL lipoproteins (beta lipoproteins) contain LDL cholesterol.
- Lipoprotein(a)
- VLDL lipoproteins (prebeta lipoproteins) contain VLDL cholesterol. High levels are found in the familial disorder hyperlipoproteinemia type IIB.
- Chylomicrons
Abnormal lipoproteins not normally present.
- Lipoprotein-X
References
- ↑ Anonymous (2024), Lipoprotein (English). Medical Subject Headings. U.S. National Library of Medicine.