Menopause: Difference between revisions

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==Treatment==
==Treatment==
[[Second-generation antidepressant]]s ([[paroxetine]], [[venlafaxine]], [[fluoxetine]]) and [[gabapentin]] may reduce [[hot flash]]es.<ref name="pmid16670414">{{cite journal| author=Nelson HD, Vesco KK, Haney E, Fu R, Nedrow A, Miller J et al.| title=Nonhormonal therapies for menopausal hot flashes: systematic review and meta-analysis. | journal=JAMA | year= 2006 | volume= 295 | issue= 17 | pages= 2057-71 | pmid=16670414 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16670414 | doi=10.1001/jama.295.17.2057 }}  [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17152139 Review in: J Fam Pract. 2006 Aug;55(8):662] </ref><ref name="pmid19332723">{{cite journal| author=Loprinzi CL, Sloan J, Stearns V, Slack R, Iyengar M, Diekmann B et al.| title=Newer antidepressants and gabapentin for hot flashes: an individual patient pooled analysis. | journal=J Clin Oncol | year= 2009 | volume= 27 | issue= 17 | pages= 2831-7 | pmid=19332723 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19332723 | doi=10.1200/JCO.2008.19.6253 | pmc=PMC2698018 }} </ref>
Hot flushes can be reduced in some women with as little as  0.014 mg of 17-<math>\beta</math>-[[estradiol]] in a daily transdermal patch.<ref name="pmid17906008">{{cite journal |author=Bachmann GA, Schaefers M, Uddin A, Utian WH |title=Lowest effective transdermal 17beta-estradiol dose for relief of hot flushes in postmenopausal women: a randomized controlled trial |journal=Obstet Gynecol |volume=110 |issue=4 |pages=771–9 |year=2007 |pmid=17906008 |doi=10.1097/01.AOG.0000284450.51264.31 |issn=}}</ref>
Hot flushes can be reduced in some women with as little as  0.014 mg of 17-<math>\beta</math>-[[estradiol]] in a daily transdermal patch.<ref name="pmid17906008">{{cite journal |author=Bachmann GA, Schaefers M, Uddin A, Utian WH |title=Lowest effective transdermal 17beta-estradiol dose for relief of hot flushes in postmenopausal women: a randomized controlled trial |journal=Obstet Gynecol |volume=110 |issue=4 |pages=771–9 |year=2007 |pmid=17906008 |doi=10.1097/01.AOG.0000284450.51264.31 |issn=}}</ref>


==References==
==References==
<references/>
<references/>

Revision as of 17:38, 15 October 2010

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Menopause is defined as "the permanent cessation of menses (menstruation)."[1]

The typical duration of symptoms is 4 years.[2]

Treatment

Second-generation antidepressants (paroxetine, venlafaxine, fluoxetine) and gabapentin may reduce hot flashes.[3][4]


Hot flushes can be reduced in some women with as little as 0.014 mg of 17--estradiol in a daily transdermal patch.[5]

References

  1. National Library of Medicine. Menopause. Retrieved on 2007-12-21.
  2. Politi MC, Schleinitz MD, Col NF (September 2008). "Revisiting the duration of vasomotor symptoms of menopause: a meta-analysis". J Gen Intern Med 23 (9): 1507–13. DOI:10.1007/s11606-008-0655-4. PMID 18521690. Research Blogging.
  3. Nelson HD, Vesco KK, Haney E, Fu R, Nedrow A, Miller J et al. (2006). "Nonhormonal therapies for menopausal hot flashes: systematic review and meta-analysis.". JAMA 295 (17): 2057-71. DOI:10.1001/jama.295.17.2057. PMID 16670414. Research Blogging. Review in: J Fam Pract. 2006 Aug;55(8):662
  4. Loprinzi CL, Sloan J, Stearns V, Slack R, Iyengar M, Diekmann B et al. (2009). "Newer antidepressants and gabapentin for hot flashes: an individual patient pooled analysis.". J Clin Oncol 27 (17): 2831-7. DOI:10.1200/JCO.2008.19.6253. PMID 19332723. PMC PMC2698018. Research Blogging.
  5. Bachmann GA, Schaefers M, Uddin A, Utian WH (2007). "Lowest effective transdermal 17beta-estradiol dose for relief of hot flushes in postmenopausal women: a randomized controlled trial". Obstet Gynecol 110 (4): 771–9. DOI:10.1097/01.AOG.0000284450.51264.31. PMID 17906008. Research Blogging.