Oseltamivir: Difference between revisions
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[[Image:Oseltamivir structure.jpg| | |||
{{Chem infobox | |||
|align=right | |||
|image=[[Image:Oseltamivir structure.jpg|center|thumb|200px]] | |||
|width=200px | |||
|molname=oseltamivir | |||
|synonyms= '''Tamiflu®''' | |||
|molformula= C<sub>16</sub>H<sub>28</sub>N<sub>2</sub>O<sub>4</sub> | |||
|molmass= 312.4045 | |||
|uses=influenza A & B | |||
|properties=sialic acid homolog, neuraminidase inhibitor | |||
|hazards=see drug interactions | |||
|iupac= see chemistry section | |||
|casnumber=204255-11-8 | |||
}} | |||
'''Oseltamivir''', or '''oseltamivir phosphate''', marketed as '''Tamiflu®''', is an acetamido cyclohexene that is a structural homolog of [[sialic acid]] and it is a [[neuraminidase]] inhibitor. It is used to treat [[influenze]] A and B infection and also is used prophylactically. The active form is the ester hydrolysed form, a carboxylate. Oseltamivir (like [[zanamivir]]) acts as a transition-state analogue inhibitor of influenza neuraminidase. | '''Oseltamivir''', or '''oseltamivir phosphate''', marketed as '''Tamiflu®''', is an acetamido cyclohexene that is a structural homolog of [[sialic acid]] and it is a [[neuraminidase]] inhibitor. It is used to treat [[influenze]] A and B infection and also is used prophylactically. The active form is the ester hydrolysed form, a carboxylate. Oseltamivir (like [[zanamivir]]) acts as a transition-state analogue inhibitor of influenza neuraminidase. | ||
Its IUPAC chemical name is ethyl (3R,4R,5S)-4-acetamido-5-amino-3-pentan-3-yloxycyclohexene-1-carboxylate and its chemical formula is C<sub>16</sub>H<sub>28</sub>N<sub>2</sub>O<sub>4</sub>. | |||
== Chemistry == | |||
Its IUPAC chemical name is ethyl (3R,4R,5S)-4-acetamido-5-amino-3-pentan-3-yloxycyclohexene-1-carboxylate and its chemical formula is C<sub>16</sub>H<sub>28</sub>N<sub>2</sub>O<sub>4</sub>, giving it a molecular mass of 312.4045 g/mol. | |||
== External links == | == External links == | ||
Revision as of 12:47, 24 March 2008
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| oseltamivir | |||||||
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| Uses: | influenza A & B | ||||||
| Properties: | sialic acid homolog, neuraminidase inhibitor | ||||||
| Hazards: | see drug interactions | ||||||
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Oseltamivir, or oseltamivir phosphate, marketed as Tamiflu®, is an acetamido cyclohexene that is a structural homolog of sialic acid and it is a neuraminidase inhibitor. It is used to treat influenze A and B infection and also is used prophylactically. The active form is the ester hydrolysed form, a carboxylate. Oseltamivir (like zanamivir) acts as a transition-state analogue inhibitor of influenza neuraminidase.
Chemistry
Its IUPAC chemical name is ethyl (3R,4R,5S)-4-acetamido-5-amino-3-pentan-3-yloxycyclohexene-1-carboxylate and its chemical formula is C16H28N2O4, giving it a molecular mass of 312.4045 g/mol.
External links
- Oseltamivir - FDA approved drug information (drug label) from DailyMed (U.S. National Library of Medicine).
- Template:MedMaster
- Template:DrugBank