Oseltamivir

(CC) Image: David E. Volk
Oseltamivir

Oseltamivir, or oseltamivir phosphate, marketed as Tamiflu®, is an acetamido cyclohexene that is a structural homolog of sialic acid and it is a neuraminidase inhibitor. It is used to treat influenze A and B infection and also is used prophylactically. The active form is the ester hydrolysed form, a carboxylate. Oseltamivir (like zanamivir) acts as a transition-state analogue inhibitor of influenza neuraminidase.

Its IUPAC chemical name is ethyl (3R,4R,5S)-4-acetamido-5-amino-3-pentan-3-yloxycyclohexene-1-carboxylate and its chemical formula is C₁₆H₂₈N₂O₄.

External links

• Oseltamivir - FDA approved drug information (drug label) from DailyMed (U.S. National Library of Medicine).
• Drug Bank at http://www.drugbank.ca/cgi-bin/getCard.cgi?CARD=DB00198.txt