Patient compliance: Difference between revisions

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imported>Robert Badgett
(New page: {{subpages}} '''Patient compliance''' is "voluntary cooperation of the patient in following a prescribed regimen."<ref>{{MeSH}}</ref> Patient compliance is a component of [[health behavio...)
 
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{{subpages}}
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'''Patient compliance''' is "voluntary cooperation of the patient in following a prescribed regimen."<ref>{{MeSH}}</ref>
'''Patient compliance''' is "voluntary cooperation of the patient in following a prescribed regimen."<ref>{{MeSH}}</ref> Improving compliance may improve health.<ref name="pmid16916809">{{cite journal |author=Wu JY, Leung WY, Chang S, ''et al'' |title=Effectiveness of telephone counselling by a pharmacist in reducing mortality in patients receiving polypharmacy: randomised controlled trial |journal=BMJ |volume=333 |issue=7567 |pages=522 |year=2006 |pmid=16916809 |doi=10.1136/bmj.38905.447118.2F}}</ref>


Patient compliance is a component of [[health behavior]].
Patient compliance is a component of [[health behavior]].
==Prevalence and epidemiology==
Many people have difficulty with taking all the medications that they have been prescribed.<ref name="pmid8492406">{{cite journal |author=Stephenson BJ, Rowe BH, Haynes RB, Macharia WM, Leon G |title=The rational clinical examination. Is this patient taking the treatment as prescribed? |journal=JAMA |volume=269 |issue=21 |pages=2779–81 |year=1993 |pmid=8492406 |doi=}}</ref> Among patients who have to take numerous drugs for their health (polypharmacy), not taking all of their medications may lead to poorer health outcomes.<ref name="pmid16790458">{{cite journal |author=Simpson SH, Eurich DT, Majumdar SR, ''et al'' |title=A meta-analysis of the association between adherence to drug therapy and mortality |journal=BMJ |volume=333 |issue=7557 |pages=15 |year=2006 |pmid=16790458 |doi=10.1136/bmj.38875.675486.55}}</ref>
23% of patients report skipping doses or cutting pills in half to make their supply last longer according to one survey.<ref> USA Today/Kaiser Family Foundation/Harvard School of Public Health Survey: the public on prescription drugs and pharmaceutical companies - kaiser family foundation. Retrieved March 10, 2008, from http://www.kff.org/kaiserpolls/pomr030408pkg.cfm.</ref> This is more common among low-income patients.
==How to detect noncompliance==
A [[systematic review]] by the [http://www.sgim.org/clinexam-rce.cfm Rational Clinical Examination] concluded that missing appointment, not improving with treatment, and counting pills are the best methods to detect non-compliance.<ref name="pmid8492406">{{cite journal |author=Stephenson BJ, Rowe BH, Haynes RB, Macharia WM, Leon G |title=The rational clinical examination. Is this patient taking the treatment as prescribed? |journal=JAMA |volume=269 |issue=21 |pages=2779–81 |year=1993 |pmid=8492406 |doi=}} [http://jama.ama-assn.org/cgi/reprint/269/21/2779 pdf]</ref>
==Methods to improve compliance==
Medications that are taken less often per day may be easier to comply with.<ref name="pmid16270428">{{cite journal |author=Treharne GJ, Lyons AC, Kitas GD |title=Adherence to medication |journal=N. Engl. J. Med. |volume=353 |issue=18 |pages=1972-4; author reply 1972-4 |year=2005 |pmid=16270428 |doi=}}</ref> Fixed-dose combination drugs can help.<ref name="pmid18288541">{{cite journal |author=Pan F, Chernew ME, Fendrick AM |title=Impact of fixed-dose combination drugs on adherence to prescription medications |journal=J Gen Intern Med |volume=23 |issue=5 |pages=611–4 |year=2008 |month=May |pmid=18288541 |doi=10.1007/s11606-008-0544-x |url=http://dx.doi.org/10.1007/s11606-008-0544-x |issn=}}</ref><ref name="pmid17563050">{{cite journal |author=Gerbino PP, Shoheiber O |title=Adherence patterns among patients treated with fixed-dose combination versus separate antihypertensive agents |journal=Am J Health Syst Pharm |volume=64 |issue=12 |pages=1279–83 |year=2007 |month=June |pmid=17563050 |doi=10.2146/ajhp060434 |url=http://www.ajhp.org/cgi/pmidlookup?view=long&pmid=17563050 |issn=}}</ref> Similarly, [[polypharmacy]] should be avoided.


==References==
==References==
<references/>
<references/>

Revision as of 04:11, 16 June 2008

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Patient compliance is "voluntary cooperation of the patient in following a prescribed regimen."[1] Improving compliance may improve health.[2]

Patient compliance is a component of health behavior.

Prevalence and epidemiology

Many people have difficulty with taking all the medications that they have been prescribed.[3] Among patients who have to take numerous drugs for their health (polypharmacy), not taking all of their medications may lead to poorer health outcomes.[4]

23% of patients report skipping doses or cutting pills in half to make their supply last longer according to one survey.[5] This is more common among low-income patients.

How to detect noncompliance

A systematic review by the Rational Clinical Examination concluded that missing appointment, not improving with treatment, and counting pills are the best methods to detect non-compliance.[3]

Methods to improve compliance

Medications that are taken less often per day may be easier to comply with.[6] Fixed-dose combination drugs can help.[7][8] Similarly, polypharmacy should be avoided.


References

  1. Anonymous (2024), Patient compliance (English). Medical Subject Headings. U.S. National Library of Medicine.
  2. Wu JY, Leung WY, Chang S, et al (2006). "Effectiveness of telephone counselling by a pharmacist in reducing mortality in patients receiving polypharmacy: randomised controlled trial". BMJ 333 (7567): 522. DOI:10.1136/bmj.38905.447118.2F. PMID 16916809. Research Blogging.
  3. 3.0 3.1 Stephenson BJ, Rowe BH, Haynes RB, Macharia WM, Leon G (1993). "The rational clinical examination. Is this patient taking the treatment as prescribed?". JAMA 269 (21): 2779–81. PMID 8492406[e] Cite error: Invalid <ref> tag; name "pmid8492406" defined multiple times with different content
  4. Simpson SH, Eurich DT, Majumdar SR, et al (2006). "A meta-analysis of the association between adherence to drug therapy and mortality". BMJ 333 (7557): 15. DOI:10.1136/bmj.38875.675486.55. PMID 16790458. Research Blogging.
  5. USA Today/Kaiser Family Foundation/Harvard School of Public Health Survey: the public on prescription drugs and pharmaceutical companies - kaiser family foundation. Retrieved March 10, 2008, from http://www.kff.org/kaiserpolls/pomr030408pkg.cfm.
  6. Treharne GJ, Lyons AC, Kitas GD (2005). "Adherence to medication". N. Engl. J. Med. 353 (18): 1972-4; author reply 1972-4. PMID 16270428[e]
  7. Pan F, Chernew ME, Fendrick AM (May 2008). "Impact of fixed-dose combination drugs on adherence to prescription medications". J Gen Intern Med 23 (5): 611–4. DOI:10.1007/s11606-008-0544-x. PMID 18288541. Research Blogging.
  8. Gerbino PP, Shoheiber O (June 2007). "Adherence patterns among patients treated with fixed-dose combination versus separate antihypertensive agents". Am J Health Syst Pharm 64 (12): 1279–83. DOI:10.2146/ajhp060434. PMID 17563050. Research Blogging.