Reserpine

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In pharmacology, reserpine is "an alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool..."[1]

Efficacy

Hypertension

Reserpine can lower the systolic blood pressure by about 8 mm Hg.[2]-

References

  1. ↑ Anonymous (2024), Reserpine (English). Medical Subject Headings. U.S. National Library of Medicine.
  2. ↑ Shamon SD, Perez MI (2009). "Blood pressure lowering efficacy of reserpine for primary hypertension.". Cochrane Database Syst Rev (4): CD007655. DOI:10.1002/14651858.CD007655.pub2. PMID 19821434. Research Blogging.
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