Transfusion reaction: Difference between revisions
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A classification has been proposed by the American Association of Blood Banks (AABB).<ref name="pmid17381620">{{cite journal |author=Sanders RP, Geiger TL, Heddle N, Pui CH, Howard SC |title=A revised classification scheme for acute transfusion reactions |journal=Transfusion |volume=47 |issue=4 |pages=621–8 |year=2007 |month=April |pmid=17381620 |doi=10.1111/j.1537-2995.2007.01163.x |url=http://www.blackwell-synergy.com/openurl?genre=article&sid=nlm:pubmed&issn=0041-1132&date=2007&volume=47&issue=4&spage=621 |issn=}}</ref> In addition, the classification below is based on [[ICD9]]. | A classification has been proposed by the American Association of Blood Banks (AABB).<ref name="pmid17381620">{{cite journal |author=Sanders RP, Geiger TL, Heddle N, Pui CH, Howard SC |title=A revised classification scheme for acute transfusion reactions |journal=Transfusion |volume=47 |issue=4 |pages=621–8 |year=2007 |month=April |pmid=17381620 |doi=10.1111/j.1537-2995.2007.01163.x |url=http://www.blackwell-synergy.com/openurl?genre=article&sid=nlm:pubmed&issn=0041-1132&date=2007&volume=47&issue=4&spage=621 |issn=}}</ref> In addition, the classification below is based on [[ICD9]]. | ||
==Immunologic== | |||
===Febrile, nonhemolytic transfusion reaction (FNHTR)=== | ===Febrile, nonhemolytic transfusion reaction (FNHTR)=== | ||
This is a minor, acute reaction suggested by negative a [[Coombs' test]], no free hemoglobin in the plasma, and no hemoglobin in the urine. | This is a minor, acute reaction suggested by negative a [[Coombs' test]], no free hemoglobin in the plasma, and no hemoglobin in the urine. | ||
| Line 15: | Line 16: | ||
ICD9: {{ICD9|518.7}} | ICD9: {{ICD9|518.7}} | ||
This is an acute reaction. | This is an acute reaction. | ||
==Nonimmunologic== | |||
===Chemical reactions=== | |||
* Hemosiderosis | |||
* Hypocalcemia from citrate toxicity | |||
* Hyperkalemia | |||
* Metabolic alkalosis and hypokalemia due to citrate | |||
===Transmission of infection=== | |||
===Other reactions=== | |||
* Hypothermia | |||
* Circulatory overload | |||
* Hypotension associated with leukoreduced blood | |||
* Transfusion-related acute lung injury (pulmonary leukoagglutinin reaction) (TRALI) | |||
==References== | ==References== | ||
<references/> | <references/> | ||
Revision as of 18:57, 6 November 2008
A classification has been proposed by the American Association of Blood Banks (AABB).[1] In addition, the classification below is based on ICD9.
Immunologic
Febrile, nonhemolytic transfusion reaction (FNHTR)
This is a minor, acute reaction suggested by negative a Coombs' test, no free hemoglobin in the plasma, and no hemoglobin in the urine.
ABO incompatibility reaction
ICD9: 999.6
This reaction usually causes acute hemolysis.
Rh incompatibility reaction
ICD9: 999.7
This reaction usually causes delayed hemolysis.
ICD9: 518.7
This is an acute reaction.
Nonimmunologic
Chemical reactions
- Hemosiderosis
- Hypocalcemia from citrate toxicity
- Hyperkalemia
- Metabolic alkalosis and hypokalemia due to citrate
Transmission of infection
Other reactions
- Hypothermia
- Circulatory overload
- Hypotension associated with leukoreduced blood
- Transfusion-related acute lung injury (pulmonary leukoagglutinin reaction) (TRALI)
References
- ↑ Sanders RP, Geiger TL, Heddle N, Pui CH, Howard SC (April 2007). "A revised classification scheme for acute transfusion reactions". Transfusion 47 (4): 621–8. DOI:10.1111/j.1537-2995.2007.01163.x. PMID 17381620. Research Blogging.