Zanamivir: Difference between revisions

From Citizendium
Jump to navigation Jump to search
imported>David E. Volk
(Chem infobox)
imported>Robert Badgett
No edit summary
 
Line 19: Line 19:


Its IUPAC chemical name is (4S,5R,6R)-5-acetamido-4-(diaminomethylideneamino)-6-[(1R,2R)-1,2,3-trihydroxypropyl]-5,6-dihydro-4H-pyran-2-carboxylic acid and its chemical formula is C<sub>12</sub>H<sub>20</sub>N<sub>4</sub>O<sub>7</sub>.
Its IUPAC chemical name is (4S,5R,6R)-5-acetamido-4-(diaminomethylideneamino)-6-[(1R,2R)-1,2,3-trihydroxypropyl]-5,6-dihydro-4H-pyran-2-carboxylic acid and its chemical formula is C<sub>12</sub>H<sub>20</sub>N<sub>4</sub>O<sub>7</sub>.
==Dosage==
According to MedMaster, "the recommended dose of RELENZA for ''treatment'' of influenza in adults and pediatric patients ages 7 years of age and older is 10 mg twice daily (approximately 12 hours apart) for 5 days." Zanamivir is administered by inhalation and is supplied at 5 mg blister per dose so 20 blisters are needed. One Relenza Diskhaler contains 20 blisters.


== Brand names ==
== Brand names ==
Line 28: Line 31:


== External links ==
== External links ==
* {{DailyMed}}
{{CZMed}}
* {{MedMaster}}
* {{DrugBank}}

Latest revision as of 12:31, 21 January 2009

This article is a stub and thus not approved.
Main Article
Discussion
Related Articles  [?]
Bibliography  [?]
External Links  [?]
Citable Version  [?]
 
This editable Main Article is under development and subject to a disclaimer.
Zanamivir structure.jpg
zanamivir
IUPAC name: see chemistry section
Synonyms: Relenza®
Formula: C12H20N4O7

 Uses: influenza A & B

 Properties: neuraminidase inhibitor

 Hazards: see drug interactions

Mass (g/mol): CAS #:
332.3098 139110-80-8


Zanamivir is a guanido-neuraminic acid that is a neuraminidase inhibitor used as an antiviral drug to treat influenza A and B.

Its IUPAC chemical name is (4S,5R,6R)-5-acetamido-4-(diaminomethylideneamino)-6-[(1R,2R)-1,2,3-trihydroxypropyl]-5,6-dihydro-4H-pyran-2-carboxylic acid and its chemical formula is C12H20N4O7.

Dosage

According to MedMaster, "the recommended dose of RELENZA for treatment of influenza in adults and pediatric patients ages 7 years of age and older is 10 mg twice daily (approximately 12 hours apart) for 5 days." Zanamivir is administered by inhalation and is supplied at 5 mg blister per dose so 20 blisters are needed. One Relenza Diskhaler contains 20 blisters.

Brand names

  • GANA
  • GNA
  • Relenza (GlaxoSmithKline)
  • ZMR
  • Zanamavir

External links

The most up-to-date information about Zanamivir and other drugs can be found at the following sites.