CD63 antigen
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In allergy and immunology, the CD63 antigen is a glycoprotein with a molecular mass of 30-60 kDa,[1] which is activated by allergic sensitization of basophils. Since basophils themselves are rare, it has proven convenient to measure their activation using flow cytometry of CD63. [2]
References
- ↑ Marcel J. Metzelaar et al. (15 February 1991), CD63 Antigen: A Novel Lysosomal Membrane Glycoprotein, Cloned by a Screening Procedure for Intracellular Antigens in Eukaryotic Cells, vol. 266, at 3239-3245
- ↑ Monneret G, Gutowski MC, Bienvenu J. (March 1999), "Detection of allergen-induced basophil activation by expression of CD63 antigen using a tricolour flow cytometric method.", Clin Exp Immunol 115 (3): 393-6