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- Depression (economics) : Add brief definition or description
- Great Depression : the severe downturn in economic activity that started in 1929 in Germany and the United States and affected many other countries.
- Depression (psychology) : Psychiatric disorder characterized by generalized melancholy, retreat from social contact, disrupted sleep patterns, akathisia, or a feeling of restlessness and increased movement, and anhedonia, or a diminished ability to experience pleasure.
- Major depressive disorder : Clinical syndrome that includes a persistent sad mood or loss of interest in activities that persists for at least 2 weeks in the absence of external precipitants.