Insulin resistance

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In medicine, insulin resistance is "diminished effectiveness of insulin in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent hyperglycemia or ketosis. Tt can be caused by the presence of insulin antibodies or the abnormalities in insulin receptors (receptor, insulin) on target cell surfaces. It is often associated with obesity; diabetic ketoacidosis; infection; and certain rare conditions."[1]

Insulin resistance (HOMA-IR) can be measured by:[2]

\text{HOMA-IR} = \frac{\text{fasting plasma glucose} * \text{fasting insulin}}{22.5}

References

  1. ↑ Anonymous, (2009) Insulin resistance (English). Medical Subject Headings. U.S. National Library of Medicine.
  2. ↑ Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC (1985). "Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man". Diabetologia 28: 412–9. PMID 3899825.
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