Lymphangiosarcoma/Definition

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Lymphangiosarcoma [r]: A malignant tumor originating from the endothelial cells of lymphatic vessels. Most lymphangiosarcomas arise in an arm secondary to radical mastectomy but they sometimes complicate idiopathic lymphedema. The lymphedema has usually been present for 6 to 10 years before malignant changes develop.

This definition is at least in part based on: Anonymous (2023), Lymphangiosarcoma (English). Medical Subject Headings. U.S. National Library of Medicine.