U1 small nuclear ribonucleoprotein/Definition

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U1 small nuclear ribonucleoprotein [r]: A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm, the U1 snRNP along with other small nuclear ribonucleoproteins (U2, U4-U6, and U5) assemble into spliceosomes that remove introns from pre-mRNA by splicing. The U1 snRNA forms base pairs with conserved sequence motifs at the 5'-splice site and recognizes both the 5'- and 3'-splice sites and may have a fundamental role in aligning the two sites for the splicing reaction.

This definition is at least in part based on: Anonymous (2023), U1 small nuclear ribonucleoprotein (English). Medical Subject Headings. U.S. National Library of Medicine.